My Cancer Molecular Information Exchange (myCMIE)

Building Digital Communities using Profile Report Content.


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1 Contextualizing

The goal of contextualizing module is to help user understand the molecular profile within the report in a visual-friendly context and get insights about the inner relationship.

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2 Connecting

The goal of connecting module is to unleash hidden states of molecular profiles, this module re-contextualizes the profile by using public databases and opens up more contexts.

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3 Clinical

My medical community provides a interactive timeline visulization of medical histories. It includes diagonoses, assays, stages and treatment information


Browser compatibility


Disclaimer: This resource is for research use only. It should not be used for emergencies or medical or professional advice.

A finding of a drug-molecular profile interaction or potentially druggable molecular profile does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or lack of a potentially druggable molecular profile does not necessarily indicate lack of effectiveness of any drug or treatment regimen. The myCMIE application tool website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.


Kowalski-Muegge Lab
Dell Medical School, University of Texas at Austin

5

Genomic

Biomarkers (optional)


Quickly to Add Rows.
Contents are always editable with double click cells

Clinical


Option 1

Examples


Option 2

Upload

    Date format is MM/DD/YYYY
    "start" and "content" columns required

Option 3

Online Editing

Please directly edit the table below to input medical history.
Double click each cell and they are all editable.


Enrichment Oncoplot


Enrichment Overlapped Genes

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All Pathways



Chromosome Location


Chromosome Map

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This module may take some time...

Drug-Gene Interaction


Prediction of drug-gene Interactions





Sample pool

Download example
Download example
Molecular data should be a table has three columns, 'gene', 'sample_id', 'value
[sample_id] must start with 'user-', such as 'user-S001'
[value] must be one of MUT or CNA
Clinical data has no limitation in column number be mut include 'sample_id' as one column


Digital twin community



                        

Input Profile

Select rows to matching by a subset of profiles
* OQL: Oncology Query Language


Digital-twin Profiles




Searching for digital twins







Match the unmatched

Pre-matching statistics


                          

                          

TCGA Community with controlled biomarkers


Post-matching statistics

Matched & Unmatched: Genomic Profile


Matched & Unmatched: Sample list

Clinical data and Alterations



Rendering

Oncoplot (IC50)


Ordered plot (IC50)




Enrichment Oncoplot (Cell line driver genes)






Tumor Micro-Environment (TME)



Download

Mutations functions: Gain or Loss?




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mRNA expression: rna_seq_v2_mrna_median_Zscores

PDX Drug response


(Query by gene symbols)


Expression Oncoplot


All oncoplot

Combined Oncoplot


Mutation methylation burden


Cancer type

Gene query

Visuals


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Clinical/Genomic Feature Explorer


Clinical-Genomic Heatmap






Loading trials

Download

Clinical trials

Loading trials

Medical History Timeline

Searching for Digital-twin Community...

My Profile


My Digital Twin Community





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We do not store data on myCMIE. Data input to run the application is removed upon closing the application.

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