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NBBC Guide

3 Input types

3.1 Overview

The NBBC app accepts input from three different levels: gene Signature-level, Gene-level, Site-level. (A) Signature-level input. The input includes popular cancer signatures, cell line molecular signatures or user-defined signatures. (B) Gene-level input. The typical use case is a quick single gene search by manual input and motif exploration with the query gene. (C) Site-level input. It applies to burden queries at the high genomic resolution, such as cancer-specific mutation sites or regions with copy number alterations.